This page discusses biochemistry learning goals, focusing on protein-ligand interactions and the immune system. Topics include immune response mechanisms, the role of signaling molecules like cGAMP, a...This page discusses biochemistry learning goals, focusing on protein-ligand interactions and the immune system. Topics include immune response mechanisms, the role of signaling molecules like cGAMP, and the importance of mRNA vaccines. It explains pathogen recognition via pattern recognition receptors, inflammasome formation involving proteins like ASC, and the activation of NLRP3 by PAMPS and DAMPS.
This page explains the remarkable diversity of T-cell receptors (TCRs) and B-cell receptors (BCRs) generated from a limited number of genes. It describes how random assortments and recombination of ge...This page explains the remarkable diversity of T-cell receptors (TCRs) and B-cell receptors (BCRs) generated from a limited number of genes. It describes how random assortments and recombination of gene segments during B cell differentiation, alongside mechanisms for TCRs, contribute to this variability. Notably, αβ T cells exhibit high diversity from the CDR3 region, while γδ T cells have a smaller repertoire.
This page provides an overview of the immune system's functionality, detailing the roles of both innate and adaptive immunity, particularly focusing on the mechanisms of B cells and T cells. Key eleme...This page provides an overview of the immune system's functionality, detailing the roles of both innate and adaptive immunity, particularly focusing on the mechanisms of B cells and T cells. Key elements include the structure and diversity of antibodies, significance of immunoglobulin domains, and the dynamics of antibody-antigen interactions.
