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- https://bio.libretexts.org/Bookshelves/Genetics/Working_with_Molecular_Genetics_(Hardison)/Unit_II%3A_Replication_Maintenance_and_Alteration_of_the_Genetic_Material/5._DNA_replication_I%3A_Enzymes_and_mechanism/Basic_Mechanisms_of_ReplicationThe part of the connecting line representing the 3’ end of the phosphodiester attached to the vertical (deoxyribose) line about 1/3 of the way along it, and the part of the connecting line representin...The part of the connecting line representing the 3’ end of the phosphodiester attached to the vertical (deoxyribose) line about 1/3 of the way along it, and the part of the connecting line representing the 5’ end of the phosphodiester is attached at the end of the vertical line.
- https://bio.libretexts.org/Courses/Coastline_College/Book-_Cells_-_Molecules_and_Mechanisms_(Wong)/10%3A_DNA/10.04%3A_Eukaryotic_ReplicationGiven the crucial nature of chromosomal replication for life to exist, it is not surprising to find that eukaryotic DNA replication is very similar to the prokaryotic process. This section will highli...Given the crucial nature of chromosomal replication for life to exist, it is not surprising to find that eukaryotic DNA replication is very similar to the prokaryotic process. This section will highlight some of the differences, which are generally elaborations on the prokaryotic version.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/05%3A_DNA/5.03%3A_The_Double_Helix_of_DNAThis page discusses the 1953 discovery of the double helix structure of DNA by Francis Crick and James D. Watson, which confirmed DNA as the physical basis of genes. This work illustrated DNA's role i...This page discusses the 1953 discovery of the double helix structure of DNA by Francis Crick and James D. Watson, which confirmed DNA as the physical basis of genes. This work illustrated DNA's role in replication and genetic transmission, leading to their Nobel Prize win in 1962.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/10%3A_Mutation/10.01%3A_Mutations_-_Causes_and_SignificanceThis page discusses DNA mutations in living cells, their types (point mutations, indels, etc.), and diseases associated with them, like sickle cell anemia. It highlights the role of mutations in evolu...This page discusses DNA mutations in living cells, their types (point mutations, indels, etc.), and diseases associated with them, like sickle cell anemia. It highlights the role of mutations in evolution, gene duplication, and translocations, along with their rarity and varying rates across species. Specifically, C. elegans has a mutation rate of approximately 2.1 x 10^-8 per base pair per generation, with males contributing more due to mitotic divisions.
- https://bio.libretexts.org/Courses/Universiti_Putra_Malaysia/ESC4103_-_Environmental_Microbiology_(Universiti_Putra_Malaysia)/05%3A_Microbial_Genetics/5.03%3A_DNA_Replication/5.3A%3A_Basics_of_DNA_ReplicationDNA replication uses a semi-conservative method that results in a double-stranded DNA with one parental strand and a new daughter strand.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/05%3A_DNA/5.06%3A_The_Meselson_-_Stahl_ExperimentThis page explains semiconservative DNA replication, where the two strands of DNA separate to serve as templates for new strands. Proposed by Watson and Crick and validated by the Meselson-Stahl exper...This page explains semiconservative DNA replication, where the two strands of DNA separate to serve as templates for new strands. Proposed by Watson and Crick and validated by the Meselson-Stahl experiment, this process ensures each daughter DNA molecule consists of one old and one new strand, resulting in an "immortal strand" passed through generations. This mechanism is observed in both bacteria such as E. coli and eukaryotic organisms during chromosome replication.
- https://bio.libretexts.org/Bookshelves/Microbiology/Microbiology_(Boundless)/07%3A_Microbial_Genetics/7.03%3A_DNA_Replication/7.3A%3A_Basics_of_DNA_ReplicationDNA replication uses a semi-conservative method that results in a double-stranded DNA with one parental strand and a new daughter strand.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Book%3A_Biochemistry_Free_For_All_(Ahern_Rajagopal_and_Tan)/07%3A_Information_Processing/7.03%3A_DNA_ReplicationThe only way to make new cells is by the division of pre-existing cells. Single-celled organisms undergo division to produce more cells like themselves, while multicellular organisms arise through div...The only way to make new cells is by the division of pre-existing cells. Single-celled organisms undergo division to produce more cells like themselves, while multicellular organisms arise through division of a single cell, generally the fertilized egg. Each time a cell divides, all of its DNA must be copied faithfully so that a copy of this information can be passed on to the daughter cell. This process is called DNA replication.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/10%3A_MutationThis page discusses DNA mutations resulting from replication errors and defective repair mechanisms. It highlights the Ames test for detecting mutagenic chemicals in organisms, the impact of ionizing ...This page discusses DNA mutations resulting from replication errors and defective repair mechanisms. It highlights the Ames test for detecting mutagenic chemicals in organisms, the impact of ionizing radiation on DNA, and the role of transposons (or "jumping genes") in generating mutations by relocating within the genome.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/05%3A_DNAThis page discusses bacterial genetic recombination methods, including transformation, conjugation, and transduction. It highlights key experiments on DNA's role as genetic material, notable discoveri...This page discusses bacterial genetic recombination methods, including transformation, conjugation, and transduction. It highlights key experiments on DNA's role as genetic material, notable discoveries in its double helix structure, and semi-conservative replication. Additionally, it mentions the importance of restriction enzymes for DNA manipulation and recent advancements in sequencing techniques that enhance genome analysis.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/13%3A_Aging/13.02%3A_TelomeresThis page discusses eukaryotic chromosomes, highlighting the role of telomeres in cellular aging and cancer proliferation, as well as potential gene therapy applications. It also covers Dolly the shee...This page discusses eukaryotic chromosomes, highlighting the role of telomeres in cellular aging and cancer proliferation, as well as potential gene therapy applications. It also covers Dolly the sheep, the first cloned mammal, whose early health issues sparked debate about the long-term effects of cloning and telomere length.
