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- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/09%3A_Regulation_of_Gene_ExpressionThis page discusses gene expression regulation in E. coli and eukaryotes, highlighting the tryptophan operon in bacteria and mechanisms like transcription, RNA processing, steroid response elements, a...This page discusses gene expression regulation in E. coli and eukaryotes, highlighting the tryptophan operon in bacteria and mechanisms like transcription, RNA processing, steroid response elements, and epigenetics in eukaryotes. It mentions techniques such as footprinting and chromatin immunoprecipitation for studying DNA-binding proteins and covers specialized topics, including cell-specific gene expression, imprinted genes, and ribozymes.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/09%3A_Regulation_of_Gene_Expression/9.01%3A_Regulation_of_Gene_Expression_in_BacteriaThis page discusses gene expression regulation in E. coli, focusing on the lac operon, which metabolizes lactose through a repressor mechanism. When lactose is present, it enables transcription by det...This page discusses gene expression regulation in E. coli, focusing on the lac operon, which metabolizes lactose through a repressor mechanism. When lactose is present, it enables transcription by detaching the repressor. The page also covers the dual control by Catabolite Activator Protein (CAP), which requires cAMP for DNA binding, allowing prioritization of glucose over lactose.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/09%3A_Regulation_of_Gene_Expression/9.02%3A_The_Tryptophan_RepressorThis page explains the regulation of tryptophan synthesis in E. coli, which involves five enzymes from a clustered operon. When tryptophan is abundant, it binds to the Trp repressor, a homodimer that ...This page explains the regulation of tryptophan synthesis in E. coli, which involves five enzymes from a clustered operon. When tryptophan is abundant, it binds to the Trp repressor, a homodimer that attaches to the operator of the operon, inhibiting transcription of the genes for enzyme production. This mechanism ensures that enzymes are not synthesized when tryptophan is already present, effectively regulating the metabolic pathway.
