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11.11: Antisense Oligodeoxynucleotides and their Therapeutic Potential
https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/11%3A_Genomics/11.11%3A_Antisense_Oligodeoxynucleotides_and_their_Therapeutic_Potential
This page discusses antisense oligonucleotides, synthetic polymers designed to inhibit protein synthesis by binding to mRNA. They work by blocking ribosome function, degrading mRNA, or preventing spli...This page discusses antisense oligonucleotides, synthetic polymers designed to inhibit protein synthesis by binding to mRNA. They work by blocking ribosome function, degrading mRNA, or preventing splicing errors. Effective therapy requires evasion of nucleases and minimal side effects, often achieved through chemical modifications and targeted delivery.

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