The page explores the fundamentals of gustation, primarily focusing on G protein-coupled receptors (GPCRs) in taste physiology. It explains the role of GPCRs in detecting sweet, umami, bitter tastes, ...The page explores the fundamentals of gustation, primarily focusing on G protein-coupled receptors (GPCRs) in taste physiology. It explains the role of GPCRs in detecting sweet, umami, bitter tastes, and the kokumi sensation. The document details the molecular mechanisms involved in taste signal transduction, receptor activation, and subsequent neural transmission leading to taste perception.