This page discusses silent mutations that do not impact phenotypes, often found in non-coding regions or due to genetic redundancy. It mentions how some mutations in essential genes can result in rece...This page discusses silent mutations that do not impact phenotypes, often found in non-coding regions or due to genetic redundancy. It mentions how some mutations in essential genes can result in recessive lethal alleles, making them difficult to detect. The text also explains the naming convention of genes based on mutant phenotypes rather than their normal functions, using the example of the white gene in fruit flies to illustrate potential confusion.
Functional genomics studies the functions of genes and proteins of the genome. This page outlines the tools and techniques used in functional genomics, including gene expression analysis through RNA s...Functional genomics studies the functions of genes and proteins of the genome. This page outlines the tools and techniques used in functional genomics, including gene expression analysis through RNA sequencing, gene silencing using miRNA and siRNA technologies, and mutational analysis.