This page discusses cytotoxic T lymphocytes (CTLs), primarily CD8+ T cells, which identify and kill infected or cancerous cells through αβ T-cell receptors and class I MHC molecules. Upon activation, ...This page discusses cytotoxic T lymphocytes (CTLs), primarily CD8+ T cells, which identify and kill infected or cancerous cells through αβ T-cell receptors and class I MHC molecules. Upon activation, CTLs expand and differentiate into effector cells with helper T cell assistance, utilizing perforin and granzymes to trigger apoptosis in targets.
This page explains how the immune system responds to antigens through B and T lymphocytes, which have specific receptors. Clonal selection leads to the activation and proliferation of B cells into pla...This page explains how the immune system responds to antigens through B and T lymphocytes, which have specific receptors. Clonal selection leads to the activation and proliferation of B cells into plasma and memory cells in lymph nodes and spleen. It details the role of dendritic cells in presenting antigens and discusses graft rejection, highlighting the differences between primary and secondary immune responses, with memory cells facilitating faster reactions in subsequent exposures.
