The document outlines the organization and packaging of DNA within eukaryotic and prokaryotic cells, focusing on chromatin structure and function. It delves into the role of nucleosomes, histones, and...The document outlines the organization and packaging of DNA within eukaryotic and prokaryotic cells, focusing on chromatin structure and function. It delves into the role of nucleosomes, histones, and higher-order chromatin folding, along with the mechanisms of chromosome packaging, such as supercoiling and the actions of topoisomerases.