This page describes cleavage as a crucial early stage of cell division in embryo development post-fertilization, differentiating between holoblastic cleavage (complete division in low-yolk eggs like f...This page describes cleavage as a crucial early stage of cell division in embryo development post-fertilization, differentiating between holoblastic cleavage (complete division in low-yolk eggs like frogs) and meroblastic cleavage (incomplete division in high-yolk eggs like birds). It highlights how meroblastic cleavage occurs in a limited cytoplasmic region, resulting in multiple nuclei and a significant yolk mass, which aids in forming a normal-sized embryo from the fertilized egg.