This page discusses the difference between mutations in somatic cells and germline cells. Somatic mutations, occurring in non-reproductive cells like liver cells, are not inherited and die with the in...This page discusses the difference between mutations in somatic cells and germline cells. Somatic mutations, occurring in non-reproductive cells like liver cells, are not inherited and die with the individual. In contrast, germline mutations in sperm and eggs can be passed to future generations, making them significant in genetic inheritance. Understanding this distinction is crucial for comprehending how genetic information is transmitted across generations.