The page details the regulatory mechanisms involved in gluconeogenesis, focusing on three key enzymes: pyruvate carboxylase, phosphoenolpyruvate carboxykinase (PEPCK), and fructose-1,6-bisphosphatase....The page details the regulatory mechanisms involved in gluconeogenesis, focusing on three key enzymes: pyruvate carboxylase, phosphoenolpyruvate carboxykinase (PEPCK), and fructose-1,6-bisphosphatase. It discusses how these enzymes are regulated through allosteric effectors and hormonal influences. The page emphasizes the critical roles these enzymes play in controlling gluconeogenesis, thereby maintaining metabolic homeostasis by responding to cellular energy demands.