The page provides an extensive overview of DNA mutations and repair mechanisms, aimed at biochemistry majors. It covers types and causes of DNA mutations, mechanisms of DNA damage, and major DNA repai...The page provides an extensive overview of DNA mutations and repair mechanisms, aimed at biochemistry majors. It covers types and causes of DNA mutations, mechanisms of DNA damage, and major DNA repair pathways, including base excision repair, nucleotide excision repair, mismatch repair, and double-strand break repair. The text also discusses the biological consequences of mutations and the importance of DNA repair in preventing diseases like cancer.
The correct DNA sequence of a gene is critical to the production of a functional protein. This page outlines how DNA mutations can affect the polypeptide's sequence. Topics include what a mutation is,...The correct DNA sequence of a gene is critical to the production of a functional protein. This page outlines how DNA mutations can affect the polypeptide's sequence. Topics include what a mutation is, how mutations can be produced through exposure to mutagens, and how mutagens are classified. Small-scale and large-scale mutations are introduced. Finally, the basic mechanisms for DNA repair of these mutations is explored.
