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- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/09%3A_Investigating_DNA/9.02%3A_BioinformaticsThe introduction discusses the significant impact of technological advances on science, particularly in generating and managing "omic" data. The complexities in understanding this data in biology and ...The introduction discusses the significant impact of technological advances on science, particularly in generating and managing "omic" data. The complexities in understanding this data in biology and bioinformatics present challenges that are addressed through new computational tools and interdisciplinary approaches.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/05%3A_Protein_Function/5.8%3A__Problems_-_Predicting_Protein_Structure_and_Function_Using_Machine_Learning_and_AI_ProgramsThe document provides exercises and instructions for using machine learning/AI algorithms to predict protein structures, functions, and interactions, as well as design proteins with specific functions...The document provides exercises and instructions for using machine learning/AI algorithms to predict protein structures, functions, and interactions, as well as design proteins with specific functions. It emphasizes the use of tools such as AlphaFold, ESMFold, and iCn3D for modeling and rendering structures and interacting domains.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/04%3A_The_Three-Dimensional_Structure_of_Proteins/4.06%3A_Intrinsically_Disordered_ProteinsThis page provides a comprehensive overview of Intrinsically Disordered Proteins (IDPs), detailing their characteristics, biological roles, structural dynamics, and relevance in health and disease. ID...This page provides a comprehensive overview of Intrinsically Disordered Proteins (IDPs), detailing their characteristics, biological roles, structural dynamics, and relevance in health and disease. IDPs are unique as they lack fixed three-dimensional structures but are involved in crucial cellular functions like molecular recognition and signaling. The page covers the experimental methods for identifying IDPs, evolutionary perspectives, and implications in disease and therapeutics.
