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- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_102_Laboratory_Manual%3A_Biology_of_Plants_and_Animals_(Ray_and_Jones)/01%3A_Chapters/1.00%3A_Lab_Safety_GuidelinesThis page details the Biology 102 Lab Safety Guidelines, emphasizing essential protocols for students. Key points include recognizing safety equipment, prohibiting food and drink, wearing suitable att...This page details the Biology 102 Lab Safety Guidelines, emphasizing essential protocols for students. Key points include recognizing safety equipment, prohibiting food and drink, wearing suitable attire, disclosing medical conditions, decontaminating workspaces, safe material handling, and proper labeling. It bans mouth pipetting and solo work, mandates reporting accidents, and requires handwashing after labs.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/20%3A_General_Science/20.06%3A_DrugsThis page outlines the drug testing process, which starts with testing numerous chemicals on lab animals and may lead to human trials through an IND application to the FDA. The human trials consist of...This page outlines the drug testing process, which starts with testing numerous chemicals on lab animals and may lead to human trials through an IND application to the FDA. The human trials consist of three phases: Phase I focuses on safety in healthy volunteers, Phase II tests efficacy and side effects in patients, and Phase III collects comprehensive safety and effectiveness data. Upon successful completion, a NDA is submitted, and the drug is branded for market release.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/12%3A_Cancer/12.12%3A_The_LD50_testThis page discusses the LD50, a key metric for assessing chemical toxicity, defined as the dose needed to kill 50% of test animals. A lower LD50 signifies higher toxicity, but results can vary by admi...This page discusses the LD50, a key metric for assessing chemical toxicity, defined as the dose needed to kill 50% of test animals. A lower LD50 signifies higher toxicity, but results can vary by administration method and species differences. Ethical concerns about animal testing have led to ongoing efforts since 2000 to replace LD50 testing with alternatives that minimize animal deaths.
