This page discusses epigenetics, which involves heritable phenotype changes without DNA sequence alteration. It covers cellular differentiation, X-inactivation, and imprinting. Converting differentiat...This page discusses epigenetics, which involves heritable phenotype changes without DNA sequence alteration. It covers cellular differentiation, X-inactivation, and imprinting. Converting differentiated cells to induced pluripotent stem cells faces challenges in reversing epigenetic changes. DNA methylation and histone modifications lead to stable gene expression changes, regulated by key players known as "writers," "erasers," and "readers" that modify or recognize epigenetic marks.