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- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/11%3A_Genomics/11.11%3A_Antisense_Oligodeoxynucleotides_and_their_Therapeutic_PotentialThis page discusses antisense oligonucleotides, synthetic polymers designed to inhibit protein synthesis by binding to mRNA. They work by blocking ribosome function, degrading mRNA, or preventing spli...This page discusses antisense oligonucleotides, synthetic polymers designed to inhibit protein synthesis by binding to mRNA. They work by blocking ribosome function, degrading mRNA, or preventing splicing errors. Effective therapy requires evasion of nucleases and minimal side effects, often achieved through chemical modifications and targeted delivery.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/05%3A_DNA/5.13%3A_DNA_RepairThis page outlines the importance of DNA repair mechanisms in living cells, detailing 130 genes involved in repair processes that counteract damage from various sources, including radiation and chemic...This page outlines the importance of DNA repair mechanisms in living cells, detailing 130 genes involved in repair processes that counteract damage from various sources, including radiation and chemicals. Key repair pathways include direct reversal, Base Excision Repair (BER), Nucleotide Excision Repair (NER), and Mismatch Repair (MMR), with specific enzymes for each.
- https://bio.libretexts.org/Courses/City_College_of_San_Francisco/Introduction_to_Genetics/09%3A_Mutation_and_VariationHumans have an interesting relationship with mutation. From our perspective, mutations can be extraordinarily useful, since mutations are need for evolution to occur. Mutation is essential for the dom...Humans have an interesting relationship with mutation. From our perspective, mutations can be extraordinarily useful, since mutations are need for evolution to occur. Mutation is essential for the domestication and improvement of almost all of our food. On the other hand, mutations are the cause of many cancers and other diseases, and can be devastating to individuals. The vast majority of mutations probably go undetected. In this section, we will examine some of the causes and effects of mutati
