This page discusses Burkitt's lymphoma, a B lymphocyte tumor caused by genetic alterations, mainly involving the c-myc proto-oncogene. In about 90% of cases, c-myc is translocated from chromosome 8 to...This page discusses Burkitt's lymphoma, a B lymphocyte tumor caused by genetic alterations, mainly involving the c-myc proto-oncogene. In about 90% of cases, c-myc is translocated from chromosome 8 to chromosome 14, resulting in excessive transcription factor production that drives uncontrolled cell division.