This page discusses cytotoxic T lymphocytes (CTLs), primarily CD8+ T cells, which identify and kill infected or cancerous cells through αβ T-cell receptors and class I MHC molecules. Upon activation, ...This page discusses cytotoxic T lymphocytes (CTLs), primarily CD8+ T cells, which identify and kill infected or cancerous cells through αβ T-cell receptors and class I MHC molecules. Upon activation, CTLs expand and differentiate into effector cells with helper T cell assistance, utilizing perforin and granzymes to trigger apoptosis in targets.
The page details the fundamentals of antibodies in biochemistry, focusing on their structure, function, and the techniques used to utilize them. Key areas include understanding antibody-antigen intera...The page details the fundamentals of antibodies in biochemistry, focusing on their structure, function, and the techniques used to utilize them. Key areas include understanding antibody-antigen interactions, exploring quantitation methods like ELISA, and discussing techniques like immunohistochemistry (IHC) used for detecting proteins in vivo.