This page discusses RNA editing, which creates differences between gene sequences and RNA, influencing protein synthesis. It details two mechanisms: Substitution Editing (changing nucleotides) and Ins...This page discusses RNA editing, which creates differences between gene sequences and RNA, influencing protein synthesis. It details two mechanisms: Substitution Editing (changing nucleotides) and Insertion/Deletion Editing (altering sequences with guide RNA). An example is the human APOB gene, where a CAA codon becomes a stop codon, affecting protein production. Additionally, defects in RNA editing are associated with human cancers and diseases like ALS, underlining its importance in biology.
