In situ hybridization (ISH) is a technique used to locate specific DNA or RNA sequences in tissues or cells, using labeled probes. It differs from immunohistochemistry, which targets proteins. ISH is ...In situ hybridization (ISH) is a technique used to locate specific DNA or RNA sequences in tissues or cells, using labeled probes. It differs from immunohistochemistry, which targets proteins. ISH is crucial for understanding gene organization and function, and includes techniques like fluorescent in situ hybridization (FISH) for chromosomal sequences. It uses labeled complementary probes and allows for precise localization and quantification of nucleic acids.
