This page discusses melanocyte-stimulating hormone (MSH) and its role in melanin production and skin pigmentation, including moles and freckles. Produced in the pituitary gland, α-MSH promotes tanning...This page discusses melanocyte-stimulating hormone (MSH) and its role in melanin production and skin pigmentation, including moles and freckles. Produced in the pituitary gland, α-MSH promotes tanning in response to UV light and has appetite-suppressing properties, which, when dysfunctional, can contribute to obesity. Additionally, synthetic MSH variants are explored for tanning effects with lower UV risk and potential applications in treating impotence.