This page discusses DNA-binding proteins such as transcription factors that bind to specific DNA sequences in gene promoters and enhancers through reversible interactions. It highlights the chromatin ...This page discusses DNA-binding proteins such as transcription factors that bind to specific DNA sequences in gene promoters and enhancers through reversible interactions. It highlights the chromatin immunoprecipitation (ChIP) technique for identifying these binding sites, which involves fixing protein-DNA interactions, fragmenting DNA, isolating complexes with antibodies, and analyzing the purified DNA fragments using methods like PCR, Southern blotting, or sequencing.
