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- https://bio.libretexts.org/Courses/Portland_Community_College/Cascade_Microbiology/12%3A_Specific_Adaptive_Host_Defenses/12.1%3A_Architecture_of_the_Immune_SystemThe two ‘arms’ of the Y-shaped antibody molecule are known as the Fab region, for “fragment of antigen binding.” The far end of the Fab region is the variable region, which serves as the site of antig...The two ‘arms’ of the Y-shaped antibody molecule are known as the Fab region, for “fragment of antigen binding.” The far end of the Fab region is the variable region, which serves as the site of antigen binding. Although the location of the J chain relative to the Fc regions of the five monomers prevents IgM from performing some of the functions of IgG, the ten available Fab sites associated with a pentameric IgM make it an important antibody in the body’s arsenal of defenses.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/05%3A_Protein_Function/5.04%3A_B._The_Innate_Immune_System_PAMPs_and_DAMPs_and_InflammationThis page discusses biochemistry learning goals, focusing on protein-ligand interactions and the immune system. Topics include immune response mechanisms, the role of signaling molecules like cGAMP, a...This page discusses biochemistry learning goals, focusing on protein-ligand interactions and the immune system. Topics include immune response mechanisms, the role of signaling molecules like cGAMP, and the importance of mRNA vaccines. It explains pathogen recognition via pattern recognition receptors, inflammasome formation involving proteins like ASC, and the activation of NLRP3 by PAMPS and DAMPS.
- https://bio.libretexts.org/Courses/Mansfield_University_of_Pennsylvania/BSC_3271%3A_Microbiology_for_Health_Sciences_Sp21_(Kagle)/14%3A_Immunology/14.02%3A_Specific_Adaptive_Host_Defenses/14.2.01%3A_Architecture_of_the_Immune_SystemThe two ‘arms’ of the Y-shaped antibody molecule are known as the Fab region, for “fragment of antigen binding.” The far end of the Fab region is the variable region, which serves as the site of antig...The two ‘arms’ of the Y-shaped antibody molecule are known as the Fab region, for “fragment of antigen binding.” The far end of the Fab region is the variable region, which serves as the site of antigen binding. Although the location of the J chain relative to the Fc regions of the five monomers prevents IgM from performing some of the functions of IgG, the ten available Fab sites associated with a pentameric IgM make it an important antibody in the body’s arsenal of defenses.
- https://bio.libretexts.org/Bookshelves/Microbiology/Microbiology_(Boundless)/11%3A_Immunology/11.08%3A_T_Cells_and_Cellular_Immunity/11.8F%3A_Adaptive_Immunity_and_the_Immunoglobulin_SuperfamilyAdaptive immunity is stimulated by exposure to infectious agents and recruits elements of the immunoglobulin superfamily.
- https://bio.libretexts.org/Courses/City_College_of_San_Francisco/Introduction_to_Microbiology_(Liu_et_al.)/22%3A_Adaptive_Immunity_I/22.04%3A_Antigen-Antibody_InteractionsThis page outlines the five key functions of antibodies in immune defense: neutralization (preventing pathogen attachment), opsonization (marking pathogens for phagocytosis), agglutination (clumping p...This page outlines the five key functions of antibodies in immune defense: neutralization (preventing pathogen attachment), opsonization (marking pathogens for phagocytosis), agglutination (clumping pathogens for clearance), complement activation (promoting inflammation and recruiting phagocytes), and antibody-dependent cell-mediated cytotoxicity (ADCC), where NK cells target larger pathogens.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Map%3A_Raven_Biology_12th_Edition/50%3A_The_Immune_System/50.03%3A_Cell-Mediated_ImmunityThe adaptive, or acquired, immune response takes days or even weeks to become established—much longer than the innate response; however, adaptive immunity is more specific to pathogens and has memory....The adaptive, or acquired, immune response takes days or even weeks to become established—much longer than the innate response; however, adaptive immunity is more specific to pathogens and has memory. Adaptive immunity is an immunity that occurs after exposure to an antigen either from a pathogen or a vaccination. This part of the immune system is activated when the innate immune response is insufficient to control an infection.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Map%3A_Raven_Biology_12th_Edition/50%3A_The_Immune_System/50.02%3A_Adaptive_ImmunityThe adaptive, or acquired, immune response takes days or even weeks to become established—much longer than the innate response; however, adaptive immunity is more specific to pathogens and has memory....The adaptive, or acquired, immune response takes days or even weeks to become established—much longer than the innate response; however, adaptive immunity is more specific to pathogens and has memory. Adaptive immunity is an immunity that occurs after exposure to an antigen either from a pathogen or a vaccination. This part of the immune system is activated when the innate immune response is insufficient to control an infection.
- https://bio.libretexts.org/Courses/Manchester_Community_College_(MCC)/Remix_of_Openstax%3AMicrobiology_by_Parker_Schneegurt_et_al/14%3A_Specific_Adaptive_Host_Defenses/14.01%3A_Architecture_of_the_Immune_SystemAdaptive immunity is defined by two important characteristics: specificity and memory. Specificity refers to the adaptive immune system’s ability to target specific pathogens, and memory refers to its...Adaptive immunity is defined by two important characteristics: specificity and memory. Specificity refers to the adaptive immune system’s ability to target specific pathogens, and memory refers to its ability to quickly respond to pathogens to which it has previously been exposed. For example, when an individual recovers from chickenpox, the body develops a memory of the infection that will specifically protect it from the causative agent if it is exposed to the virus again later.
- https://bio.libretexts.org/Courses/Prince_Georges_Community_College/PGCC_Microbiology/06%3A_Immunology/6.03%3A_Adaptive_ImmunityThe adaptive, or acquired, immune response takes days or even weeks to become established—much longer than the innate response; however, adaptive immunity is more specific to pathogens and has memory....The adaptive, or acquired, immune response takes days or even weeks to become established—much longer than the innate response; however, adaptive immunity is more specific to pathogens and has memory. Adaptive immunity is an immunity that occurs after exposure to an antigen either from a pathogen or a vaccination. This part of the immune system is activated when the innate immune response is insufficient to control an infection.
- https://bio.libretexts.org/Courses/Folsom_Lake_College/BIOL_440%3A_General_Microbiology_(Panoutsopoulos)/06%3A_The_Immune_System_Nonspecific_and_Specific_Defenses/6.03%3A_Specific_Adaptive_Host_Defenses/6.3.01%3A_Architecture_of_the_Immune_SystemAdaptive immunity is defined by two important characteristics: specificity and memory. Specificity refers to the adaptive immune system’s ability to target specific pathogens, and memory refers to its...Adaptive immunity is defined by two important characteristics: specificity and memory. Specificity refers to the adaptive immune system’s ability to target specific pathogens, and memory refers to its ability to quickly respond to pathogens to which it has previously been exposed. For example, when an individual recovers from chickenpox, the body develops a memory of the infection that will specifically protect it from the causative agent if it is exposed to the virus again later.
- https://bio.libretexts.org/Courses/North_Central_State_College/BIOL_1550%3A_Microbiology_(2025)/22%3A_Adaptive_Immunity_I/22.01%3A_Adaptive_Immune_Defenses_-_OverviewAdaptive immunity is defined by two important characteristics: specificity and memory. Specificity refers to the adaptive immune system’s ability to target specific pathogens, and memory refers to its...Adaptive immunity is defined by two important characteristics: specificity and memory. Specificity refers to the adaptive immune system’s ability to target specific pathogens, and memory refers to its ability to quickly respond to pathogens to which it has previously been exposed. For example, when an individual recovers from chickenpox, the body develops a memory of the infection that will specifically protect it from the causative agent if it is exposed to the virus again later.
