12.0: Overview of RNA Processing
- Page ID
- 9992
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RNA processing refers to any covalent modification to the RNA that occurs after transcription. This includes specific cleavage, addition of nucleotides, methylation or other modification of the nucleotides, and removal of introns by splicing.
RNA | Precursor | Modification | Addition | Cleavage | Splicing |
---|---|---|---|---|---|
mRNA | pre‑mRNA (hnRNA) | methylation on 2'‑OH of ribose | 5' cap 3' poly A | cut at site for poly A; excise viral mRNA | remove introns |
rRNA | pre‑rRNA | methylation on 2'OH of ribose | no | excise products fr. precursor | remove introns |
tRNA | pre‑tRNA | extensive and varied | CCA to 3' end | yes | remove introns |
snRNAs | ? | ? | 5' cap | ? | ? |