4: Pulmonary System

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By Drs. Ingrid Waldron, Lori Spindler, and Jennifer Doherty, Dept of Biology, University of Pennsylvania, CC-BY-NC 4.0.

This minds-on, hands-on activity begins with analysis and discussion questions that develop student understanding of homeostasis and negative feedback, the difference between negative and positive feedback, and the cooperation between the respiratory and circulatory systems to provide O₂ and remove CO₂for cells all over the body. Then, students carry out and analyze an experiment which investigates how the rate and depth of breathing are affected by negative feedback regulation of blood levels of CO₂ and O₂. Finally, students formulate a question concerning the effects of exercise on breathing, design and carry out a relevant experiment, analyze and interpret their data, and relate their results to homeostasis during exercise.

4.1: Breathing Lab Protocol
Homeostasis refers to the maintenance of relatively constant internal conditions. For example, your body maintains a relatively constant body temperature even when the external environment gets colder or hotter. All the cells in your body need energy to do their work. The energy for most cellular processes is provided by ATP molecules. Most of the ATP in your cells is produced by cellular respiration which uses O2 and produces CO2.
4.2: Breathing Lab Teaching Preparation Notes
This minds-on, hands-on activity begins with analysis and discussion questions that develop student understanding of homeostasis and negative feedback, the difference between negative and positive feedback, and the cooperation between the respiratory and circulatory systems to provide O2 and remove CO2 for cells all over the body.