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Biology LibreTexts

12.0: Overview of RNA Processing

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  • RNA processing refers to any covalent modification to the RNA that occurs after transcription. This includes specific cleavage, addition of nucleotides, methylation or other modification of the nucleotides, and removal of introns by splicing.

    RNA Precursor Modification Addition Cleavage Splicing
    mRNA pre‑mRNA (hnRNA) methylation on 2'‑OH of ribose 5' cap 3' poly A cut at site for poly A; excise viral mRNA remove introns
    rRNA pre‑rRNA methylation on 2'OH of ribose no excise products fr. precursor remove introns
    tRNA pre‑tRNA extensive and varied CCA to 3' end yes remove introns
    snRNAs ? ? 5' cap ? ?