15.1: New terminology


Terminology of the theory of disease is not completely consistent in the epidemiological literature, but we will use it consistently as follows.

Virulence: How much or how quickly a pathogen harms its host. Often symbolized as alpha, $$\alpha$$, in disease equations. Example: if one-tenth of infected organisms die in a particular time period, and everything is random, $$\alpha$$ = 1/10.

Infectivity: How readily a pathogen arrives at and invades a new host. Often symbolized as beta, $$\beta$$, in disease equations. Example: in an otherwise uninfected population, if each infected host is expected to infect three others in a particular time period, $$\beta$$ = 3.

Basic reproductive number: In an otherwise uninfected population, how many new infections an infected individual is expected to produce during the duration of the infection. Often symbolized as $$R_0$$ in disease equations, and pronounced “are not.” This is a crucial number; if $$R_0$$ is greater than 1, the disease will spread through the population, while if $$R_0$$ is less than 1, the disease will die out.

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