23.5: Further Reading, Tools and Techniques, Bibliography
- Page ID
- 41062
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- Becker, S. A. and B. O. Palsson (1908). Context-Specific Metabolic Networks Are Consistent with Experiments. PLoS Computational Biology 4(5): e1000082.
– If gene expression lower than some threshold, turn the gene off in the model.
- Shlomi, T., M. N. Cabili, et al. (1908). Network-based prediction of human tissue-specific metabolism.
Nat Biotech 26(9): 1003-1010.
- Nested optimization problem.
- First, standard FBA
- Second, maximize the number of enzymes whose predicted flux activity is consistent with their measured expression level